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Latent Space: AI for Science
AINews: Weekday Roundups
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The /wayfinder Skill: Navigating the “Fog of War” of Planning
Matt Pocock tells us about his /wayfinder skill, for greenfield projects or for when the way forward is unclear.
18 hrs ago
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Richard MacManus
57
2
Frontier Model Cost and Open-Weights Popularity is Driving Demand for Model Routing
Glean CEO Arvind Jain explains why model routing helps control AI costs for organizations, and how human feedback loops at scale improve its routing…
Aug 18
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Richard MacManus
56
4
React for Agents: Astro Creator Brings Hooks to his Meta-Harness, Flue
Flue 2 takes its inspiration from React. Creator Fred Schott, of Astro fame, tells Latent Space why he added hooks and why agents are defined by their…
Aug 15
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Richard MacManus
41
1
4
🔬The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery
Pharma is suddenly paying for Bio × AI tools, and Chai is leading the pack with four deals closed this summer. Cofounder Matt McPartlon and Product…
Aug 11
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RJ Honicky
40
1:35:19
Unpacking ChatGPT Work: the Agent for a Billion Users
An external reconstruction of how Memory, Proactivity, Scheduling, Browser Use, Plugins, Skills and Tools work in the new ChatGPT Work.
Aug 4
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Shlok Khemani
110
2
5
The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten
Baseten just raised a $13B Series F and is now one of the leading kings of inference engineering. We go into everything you need to know for…
Aug 3
63
2
1
1:41:28
July 2026
Ontologies Are So Back: Why AI Agents Are Reviving the Semantic Web
AI engineers are rediscovering ontologies as a way to keep probabilistic agents inside deterministic boundaries.
Jul 30
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Richard MacManus
147
2
14
Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI
OpenAI's core product engineering lead on how they are building ChatGPT Work to make AGI accessible to all of humanity: Sites, OpenClaw, Memory…
Jul 28
66
2
2
1:09:27
Inside the Model Factory — Eiso Kant, Poolside AI
Poolside's co-CEO on how his small team of top researchers built a model factory capable of training Laguna S - a 118B MOE beating Thinky's ~1T open…
Jul 23
42
1
1:54:33
🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)
Xaira Therapeutics is all in on data generation for model building! We talk with Bo Wang and Ci Chu about how and why.
Jul 21
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RJ Honicky
47
1
1:29:46
🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences
Lila is betting that science, not the internet, is the last untapped source of training data. We went to find out what that actually looks like in a…
Jul 16
44
2
1
1:41:04
5 Trends That Defined AI Engineering at World’s Fair 2026
At this year's AIE World’s Fair, AI engineering entered a new phase: building systems around agents, rather than just building with agents.
Jul 14
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Richard MacManus
92
3
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