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Latent Space: AI for Science
AINews: Weekday Roundups
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Bitter Lessons in Venture vs Growth: Anthropic vs OpenAI, Noam Shazeer, World Labs, Thinking Machines, Cursor, ASIC Economics — Martin…
We sit down with a16z's AI investing leaders for a wide ranging conversation about what the heck going on.
Feb 19
12
1
55:18
Owning the AI Pareto Frontier — Jeff Dean
From rewriting Google’s search stack in the early 2000s to reviving sparse trillion-parameter models and co-designing TPUs with frontier ML research…
Feb 12
34
3
6
1:23:30
🔬Beyond AlphaFold: How Boltz is Open-Sourcing the Future of Drug Discovery
Inside Boltz, AlphaFold’s Legacy, and the Tools Powering Next-Gen Molecular Discovery
Feb 12
18
1
1:21:06
The Scientist and the Simulator
LLMs (alone) won’t cure cancer
Feb 10
•
Melissa
78
12
1
Experts Have World Models. LLMs Have Word Models.
Most expert work isn’t “produce a probable artifact”; it's "choose a good move considering other agents, guessing hidden state". LLMs default to…
Feb 7
•
Ankit Maloo
94
9
8
The First Mechanistic Interpretability Frontier Lab — Myra Deng & Mark Bissell of Goodfire AI
From Palantir and Two Sigma to building Goodfire into the poster-child for actionable mechanistic interpretability, Mark Bissell (Member of Technical…
Feb 6
11
2
1:08:01
January 2026
It's Time to Science
Why the time is right to start the world's first dedicated AI for Science podcast, and why AI Engineers should care
Jan 28
•
swyx (Shawn)
47
5
3
🔬 Automating Science: World Models, Scientific Taste, Agent Loops — Andrew White
Editor’s note: Welcome to our new AI for Science pod, with your new hosts RJ and Brandon!
Jan 28
3
1:13:55
Scaling without Slop
We've been quiet — announcing our 2026 plans! The State of Latent Space is here.
Jan 23
•
swyx (Shawn)
59
12
1
Captaining IMO Gold, Deep Think, On-Policy RL, Feeling the AGI in Singapore — Yi Tay
From shipping Gemini Deep Think and IMO Gold to launching the Reasoning and AGI team in Singapore, Yi Tay has spent the last 18 months living through…
Jan 23
4
1:32:04
Brex’s AI Hail Mary — With CTO James Reggio
From building internal AI labs to becoming CTO of Brex, James Reggio has helped lead one of the most disciplined AI transformations inside a real…
Jan 17
1:13:26
Full Story of Brex’s AI Hail Mary
Inside Brex’s $500M+ (ARR) AI-Fueled Comeback
Jan 17
•
Allen Park
39
1
1
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